The Valve of Hyaluronic Binding Selection (PICSI) in Improving IVF Outcome



Status:Completed
Conditions:Women's Studies, Infertility
Therapuetic Areas:Reproductive
Healthy:No
Age Range:18 - 42
Updated:4/21/2016
Start Date:March 2013
End Date:June 2014

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The investigators would like to assess whether selecting mature sperm using PICSI (selecting
for sperm that bind hyaluronan) can optimize the IVF outcome of ICSI .

Aim

1. Primary outcome: To compare routine sperm selection using ICSI with sperm selection
using PICSI plates in terms of implantation and fertilization rates for couples with
male factor fertility

2. Secondary outcome : To compare live birth rates ,ongoing pregnancies and miscarriage
rates for couples with male factor infertility using routine sperm selection with ICSI
compared to using PICSI plates for sperm selection

Hypothesis:

Sperm selected for ICSI using (PICSI) will reveal increased implantation rates in comparison
to sperm selected for conventional ICSI


Inclusion Criteria:

- In order to participate in the study women must be 42 years old or younger and suffer
from male factor infertility however they may have other causes for their infertility

- male factor infertility as defined by one or more of the following sperm parameters:
<20 Million /ml sperm concentration < 30% normal morphology < 3% Kruger morphology <
50% motility sion Criteria:
We found this trial at
1
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New York, New York 10019
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New York, NY
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