Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Breast Cancer, Cancer, Chronic Pain, Orthopedic |
| Therapuetic Areas: | Musculoskeletal, Oncology, Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 21 - 99 |
| Updated: | 4/21/2016 |
| Start Date: | August 2013 |
| End Date: | May 2016 |
For post-menopausal women diagnosed with hormone-receptor positive breast cancer tumors,
aromatase inhibitors (AIs) are the standard adjuvant hormone treatment to prolong
disease-free survival and time-to-recurrence. Unfortunately, joint pain/stiffness/achiness
(arthralgia) is a common side-effect of AIs. This "proof-of-concept" study explores how an
evidence-based physical activity (PA) program- the Arthritis Foundation's Walk with Ease
(WWE) program- can be adapted for breast cancer survivors on AI therapy to: 1) Help them
maintain or achieve recommended levels of PA, 2) reduce their joint pain/stiffness/achiness,
and 3) thereby enable them to remain on AI therapy as prescribed.
aromatase inhibitors (AIs) are the standard adjuvant hormone treatment to prolong
disease-free survival and time-to-recurrence. Unfortunately, joint pain/stiffness/achiness
(arthralgia) is a common side-effect of AIs. This "proof-of-concept" study explores how an
evidence-based physical activity (PA) program- the Arthritis Foundation's Walk with Ease
(WWE) program- can be adapted for breast cancer survivors on AI therapy to: 1) Help them
maintain or achieve recommended levels of PA, 2) reduce their joint pain/stiffness/achiness,
and 3) thereby enable them to remain on AI therapy as prescribed.
Inclusion Criteria:
- Taking an aromatase inhibitor as adjuvant treatment for State I, II, or II breast
cancer for at least 4 weeks
- Experiencing more than mild joint pain/symptoms
- 21 or older
- have permission from physician to engage in moderate intensity physical activity
Exclusion Criteria:
- Undergoing chemotherapy and/or radiation therapy at any time during the study period
- Scheduled for major surgery during the study period
- Presently engaged in high levels of physical activity on a daily basis
- Less than 21 years of age
- Unable to walk or engage in moderate intensity physical activity
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