Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma



Status:Terminated
Conditions:Pneumonia, Hematology
Therapuetic Areas:Hematology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:19 - Any
Updated:4/21/2016
Start Date:May 2013
End Date:February 2015

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The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and
E) on the development of coagulation derangements and nosocomial pneumonia after severe
trauma in patients.


Inclusion Criteria:

- Adult trauma patients admitted to the emergency department at the University of
Alabama at Birmingham Hospital

- Blunt or penetrating injury

- UAB highest trauma activation

Exclusion Criteria:

- Age < 19 years of age

- Patients with known bleeding diathesis or who are concurrently taking anticoagulant
medication

- Patients with known liver disease

- Minor patients

- Pregnant patients (known or suspected pregnancy)

- Patients who are incarcerated

- Patients who lack a surrogate
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