Assessment of Renal Function in Cirrhotic Patients



Status:Recruiting
Conditions:Renal Impairment / Chronic Kidney Disease, Gastrointestinal
Therapuetic Areas:Gastroenterology, Nephrology / Urology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:December 2010
End Date:December 2015
Contact:Erin Fassett, RN
Email:Erin.Fassett@baylorhealth.edu
Phone:817-922-7667

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Trial Summary
Trial Overview
Inclusion Criteria

Assessment of Renal Function in Cirrhotic Patients -A Comparison of Cystatin C and Creatinine Based Calculations to 125I-iothalamate

The purpose of this study is to help determine whether cystatin C is a more sensitive
laboratory measurement for renal function in cirrhotic patients.

Serum cystatin C, creatinine clearance based calculations, and 125I-Iothalamate clearance
(Glofil) will be obtained in 220 patients with cirrhosis. Utilizing this information, the
correlation between cystatin C and 125I-Iothalamate clearance will be obtained. In addition,
the current serum creatinine based calculations and true creatinine clearance will also be
correlated with 125I-Iothalamate clearance. The results of this study should help to
determine whether serum cystatin C is a more sensitive laboratory measurement of renal
function in patients with cirrhosis.

Inclusion Criteria:

- over 18 undergoing evaluation for a liver transplant

Exclusion Criteria:

- known allergy or sensitivity to 125I-Iothalamate
We found this trial at
1
site
Baylor All Saints Medical Center at Fort Worth
Fort Worth, Texas 76104
Phone: 214-820-7755
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Fort Worth, TX
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