Increasing the Removal of Protein-Bound Solutes During Extended Hours Hemodialysis

Conditions:Renal Impairment / Chronic Kidney Disease
Therapuetic Areas:Nephrology / Urology
Age Range:18 - 85
Start Date:July 2013
End Date:December 2016
Contact:tim meyer, md

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Hemodialysis keeps patients with renal failure alive but does not restore normal health.
Retention of chemicals that bind to plasma proteins and are therefore poorly removed by
dialysis may contribute to ill health in patients receiving conventional treatment. This
proposal will test the effect of a new method designed to improve the removal of
protein-bound solutes during dialysis. The effects on blood chemical levels of two different
dialysis prescriptions will be tested in patients already undergoing nocturnal in-center
hemodialysis three times weekly.

Inclusion Criteria:

- stable on nocturnal in-center dialysis located close to Stanford University and VA
Palo Alto

Exclusion Criteria:

- recent use of antibiotics

- gastrointestinal disease
We found this trial at
450 Serra Mall
Stanford, California 94305
(650) 723-2300
Principal Investigator: timothy w meyer, md
Phone: 650-852-3314
Stanford University Stanford University, located between San Francisco and San Jose in the heart of...
Stanford, CA
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Redwood City, California 94063
Phone: 650-852-3314
Redwood City, CA
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