Increasing the Removal of Protein-Bound Solutes During Extended Hours Hemodialysis
| Status: | Recruiting |
|---|---|
| Conditions: | Renal Impairment / Chronic Kidney Disease |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | 18 - 85 |
| Updated: | 4/21/2016 |
| Start Date: | July 2013 |
| End Date: | December 2016 |
| Contact: | tim meyer, md |
| Phone: | 650-852-3314 |
Hemodialysis keeps patients with renal failure alive but does not restore normal health.
Retention of chemicals that bind to plasma proteins and are therefore poorly removed by
dialysis may contribute to ill health in patients receiving conventional treatment. This
proposal will test the effect of a new method designed to improve the removal of
protein-bound solutes during dialysis. The effects on blood chemical levels of two different
dialysis prescriptions will be tested in patients already undergoing nocturnal in-center
hemodialysis three times weekly.
Retention of chemicals that bind to plasma proteins and are therefore poorly removed by
dialysis may contribute to ill health in patients receiving conventional treatment. This
proposal will test the effect of a new method designed to improve the removal of
protein-bound solutes during dialysis. The effects on blood chemical levels of two different
dialysis prescriptions will be tested in patients already undergoing nocturnal in-center
hemodialysis three times weekly.
Inclusion Criteria:
- stable on nocturnal in-center dialysis located close to Stanford University and VA
Palo Alto
Exclusion Criteria:
- recent use of antibiotics
- gastrointestinal disease
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450 Serra Mall
Stanford, California 94305
Stanford, California 94305
(650) 723-2300
Principal Investigator: timothy w meyer, md
Phone: 650-852-3314
Stanford University Stanford University, located between San Francisco and San Jose in the heart of...
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