Lifestyle Physical Activity for People With COPD

People with chronic obstructive pulmonary disease (COPD) experience a gradual decline in
physical activity (PA). Exercise training in a structured pulmonary rehabilitation program
can generate substantial gains in functional capacity, but increases in functional capacity
do not necessarily lead to improvements in daily PA. The proposed study will examine the
effects of a lifestyle physical activity intervention designed to increase PA in people with
moderate and severe COPD. The intervention includes a combination of (a) structured
laboratory-based exercises with a self-efficacy enhancing intervention, (b) structured
home-based exercises and (c) lifestyle physical activities performed at home. The
intervention gradually transitions subjects from the structured laboratory-based exercises
that focus on walking and circuit training to fully integrated lifestyle physical activities
that integrate structured home-based exercises and lifestyle physical activities into daily
life. The purpose of this preliminary study is to examine the effects of a program that
includes two-months of structured lab-based training and subjects will be followed for a
total of 18 weeks.

Inclusion Criteria:

- 55 years or older

- Moderate to severe COPD (FEV1 < 80% and > 30% predicted; FEV1/FVC <70%) as the primary
health problem

- Sedentary (less than 30 minutes of moderate activity 3 days/week)

Exclusion Criteria:

- No acute exacerbations or major illnesses requiring hospitalization in the last 8
weeks.

- No history of other major lung diseases as primary pulmonary problem, history of a
recent heart attack or recent onset of chest pains with activity or increasing
episodes of chest pain (unstable angina).

- No other health problems or mobility problems that limit physical activity.

- No child bearing potential