Open Label Study of Long Term Evaluation Against LDL-C Trial-2



Status:Completed
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 85
Updated:11/4/2018
Start Date:April 23, 2013
End Date:May 18, 2018

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A Multicenter, Controlled, Open-label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of AMG 145-2

This study will contribute to the evaluation of long-term safety, tolerability and efficacy
of evolocumab (AMG 145) in subjects with hyperlipidemia and subjects with mixed dyslipidemia.


Inclusion Criteria:

- Complete a qualifying evolocumab (AMG 145) parent study

Exclusion Criteria:

- Experienced a treatment-related serious adverse event that led to IP discontinuation
in the parent study

- Have an unstable medical condition, in the judgment of the investigator

- Known sensitivity to any of the products to be administered during dosing

- Currently enrolled in another investigational device or drug study (excluding
evolocumab (AMG 145) parent study), or less than 30 days since ending another
investigational device or drug study(s),or receiving other investigational agent(s)
We found this trial at
108
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Newport Beach, California 92660
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Akron, OH
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Bangor, ME
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Beverly Hills, California 90211
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Cadiz, OH
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Camperdown,
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Charleston, South Carolina 29412
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Chicago, IL
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Duncansville, Pennsylvania 16635
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Huntington Beach, California 92646
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Indianapolis, IN
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Mission Viejo, California 92691
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Monroe, LA
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Mount Pleasant, South Carolina 29464
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Olive Branch, Mississippi 38654
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Spring Valley, California 91978
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Thousand Oaks, California 91360
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