Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear Stress Test



Status:Completed
Conditions:Peripheral Vascular Disease, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:5/5/2014
Start Date:March 2006
End Date:December 2009
Contact:Victor H Shin, MD
Email:vshinmd@gmail.com
Phone:917-572-7939

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Trial Summary
Trial Overview
Inclusion Criteria
To compare the efficacy of 16-row multi-detector CT (MDCT) with standard myocardial
perfusion imaging in detecting coronary artery disease (CAD) in patients without a
previously established diagnosis of CAD.

Nuclear stress testing is currently the established non-invasive modality in detecting
flow-obstructing coronary artery disease (CAD).

Recently, multi-detector CT (MDCT) has emerged as a new modality that offers a non-invasive
means to directly visualize coronary anatomy and any CAD. Studies have shown that MDCT has
excellent sensitivity and a high negative predictive value in detecting significant CAD.

The purpose of this study is to compare MDCT with nuclear stress testing for detecting CAD
in previously undiagnosed patients.

Inclusion Criteria:

- Referred for a clinical indicated stress SPECT MPI

- Adequate IV access in both arms

Exclusion Criteria:

- History of coronary angioplasty or stent placement

- History of coronary bypass surgery

- Angiographic history of flow-limiting CAD

- Documented history of elevated cardiac markers

- Documented history of injury or infarct on ECG

- Absence of sinus rhythm

- Current history of renal insufficiency

- Known allergy to contrast dye

- Pregnant
We found this trial at
1
site
Providence Veterans Affairs Medical Center
830 Chalkstone Avenue
Providence, Rhode Island 02908
?
mi
from
Providence, RI
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