Effectiveness and Safety of INGN 201 in Combination With Chemotherapy Versus Chemotherapy Alone



Status:Recruiting
Conditions:Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:4/2/2016
Contact:Introgen Therapeutics, Inc.
Email:clinicaltrials@introgen.com
Phone:866.631.4646

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There is a need for more treatment options for patients with recurrent squamous cell cancer
of the head and neck (SCCHN). These tumors usually have a variety of genetic defects that
include disruption of the p53 pathway, a pathway that would ordinarily work to prevent the
development of tumors. In this study the transfer of the p53 gene to tumor cells using a
modified adenovirus (INGN 201) in combination with chemotherapy (cisplatin and fluorouracil)
will be compared to chemotherapy with cisplatin and fluorouracil in patients who have failed
surgery and radiotherapy.


- 18 years or older

- Must have had radiation treatment

- Eligible for chemotherapy

- Not eligible for surgery
We found this trial at
8
sites
Aurora, Colorado 80045
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Little Rock, Arkansas 72202
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Little Rock, AR
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Baltimore, Maryland 21204
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Columbia, South Carolina 29209
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Dallas, TX
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Houston, TX
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Louisville, Kentucky 40202
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Louisville, KY
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Miami, FL
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