Quality of Life of HIV-infected Participants Switched to Raltegravir Versus Other Antiretroviral Regimens (MK-0518-266)



Status:Completed
Conditions:HIV / AIDS
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:10/19/2013
Start Date:November 2012
End Date:October 2013
Contact:Toll Free Number
Phone:1-888-577-8839

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Quality of Life of HIV-infected Patients Switched to Raltegravir Versus Other Antiretroviral Regimens


This is a multi-center, longitudinal observational study of adult human immunodeficiency
virus (HIV) participants at academic and community-based practices in the United States who
are switching from first-line to second-line therapy. The study's primary hypothesis is that
HIV participants switching to raltegravir-based regimens will have better Medical Outcomes
Study-HIV (MOS-HIV) Health Survey scores than participants switched to non-nucleoside
reverse transcriptase inhibitor (NNRTI)-based or protease inhibitor (PI)-based regimens.


Inclusion Criteria:

- Clinical diagnosis of HIV

- Switching antiretroviral regimen(s) for the first time at the start of the study

Exclusion Criteria:

- Currently pregnant

- Presence of active tuberculosis, Hepatitis B, and/or Hepatitis C and receiving
treatment for the condition(s) during the study period

- Presence of active pneumonia or other signs of opportunistic infections at the start
of the study

- Currently participating in a clinical trial
We found this trial at
47
sites
1222
mi
from 91732
Dallas, TX
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1919
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Atlanta, GA
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1209
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Austin, TX
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354
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from 91732
Berkeley, CA
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1960
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Berkley, MI
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2144
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from 91732
Brandon, FL
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2377
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from 91732
Camden, NJ
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Charlotte, North Carolina 28205
2104
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from 91732
Charlotte, NC
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303 East Superior Street
Chicago, Illinois 60613
1730
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from 91732
Chicago, IL
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1730
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from 91732
Chicago, IL
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1880
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Cincinnati, OH
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1225
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Dallas, TX
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2315
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Fort Lauderdale, FL
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2105
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Gainesville, FL
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2497
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Hartford, CT
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1838
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Hobson City, AL
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1357
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Houston, TX
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1352
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from 91732
Houston, TX
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1349
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from 91732
Houston, TX
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29
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Irvine, CA
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1459
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Little Rock, AR
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22
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Long Beach, CA
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2175
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Lynchburg, VA
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2320
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from 91732
Miami, FL
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2320
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Miami, FL
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2316
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from 91732
Miami Gardens, FL
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1917
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Midland, MI
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1722
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Milwaukee, WI
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2441
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Mount Vernon, NY
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1378
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Nassau Bay, TX
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2422
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Newark, NJ
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2179
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Orange City, FL
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2185
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Orlando, FL
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1810
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Pensacola, FL
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1932
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Perrysburg, OH
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2218
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Raleigh, NC
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363
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Sacramento, CA
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366
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Sacramento, CA
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2146
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Sarasota, FL
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2131
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Savannah, GA
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961
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Seattle, WA
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1559
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St. Louis, MO
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1573
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St. Louis, MO
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2134
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Tampa, FL
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Washington, District of Columbia 20009
2281
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Washington,
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2314
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from 91732
Wilton Manors, FL
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2540
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from 91732
Worcester, MA
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