Quality of Life of HIV-infected Participants Switched to Raltegravir Versus Other Antiretroviral Regimens (MK-0518-266)



Status:Completed
Conditions:HIV / AIDS
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:10/19/2013
Start Date:November 2012
End Date:October 2013
Contact:Toll Free Number
Phone:1-888-577-8839

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Quality of Life of HIV-infected Patients Switched to Raltegravir Versus Other Antiretroviral Regimens


This is a multi-center, longitudinal observational study of adult human immunodeficiency
virus (HIV) participants at academic and community-based practices in the United States who
are switching from first-line to second-line therapy. The study's primary hypothesis is that
HIV participants switching to raltegravir-based regimens will have better Medical Outcomes
Study-HIV (MOS-HIV) Health Survey scores than participants switched to non-nucleoside
reverse transcriptase inhibitor (NNRTI)-based or protease inhibitor (PI)-based regimens.


Inclusion Criteria:

- Clinical diagnosis of HIV

- Switching antiretroviral regimen(s) for the first time at the start of the study

Exclusion Criteria:

- Currently pregnant

- Presence of active tuberculosis, Hepatitis B, and/or Hepatitis C and receiving
treatment for the condition(s) during the study period

- Presence of active pneumonia or other signs of opportunistic infections at the start
of the study

- Currently participating in a clinical trial
We found this trial at
47
sites
726
mi
from
Cincinnati, OH
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801
mi
from
Atlanta, GA
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511
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from
Austin, TX
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1330
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from
Berkeley, CA
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838
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from
Berkley, MI
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1123
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from
Brandon, FL
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1227
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from
Camden, NJ
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Charlotte, North Carolina 28205
960
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from
Charlotte, NC
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303 East Superior Street
Chicago, Illinois 60613
611
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from
Chicago, IL
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609
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from
Chicago, IL
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347
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from
Dallas, TX
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350
mi
from
Dallas, TX
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1307
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from
Fort Lauderdale, FL
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1049
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from
Gainesville, FL
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1358
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from
Hartford, CT
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729
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from
Hobson City, AL
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569
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from
Houston, TX
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571
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from
Houston, TX
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566
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from
Houston, TX
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1152
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from
Irvine, CA
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367
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from
Little Rock, AR
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1171
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from
Long Beach, CA
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1020
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from
Lynchburg, VA
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1321
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from
Miami, FL
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1321
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from
Miami, FL
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1312
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from
Miami Gardens, FL
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817
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from
Midland, MI
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630
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from
Milwaukee, WI
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1296
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from
Mount Vernon, NY
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587
mi
from
Nassau Bay, TX
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1276
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from
Newark, NJ
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1128
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from
Orange City, FL
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1143
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from
Orlando, FL
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787
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from
Pensacola, FL
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798
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from
Perrysburg, OH
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1067
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from
Raleigh, NC
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1281
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from
Sacramento, CA
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1283
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from
Sacramento, CA
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1141
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from
Sarasota, FL
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1024
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from
Savannah, GA
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1410
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from
Seattle, WA
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404
mi
from
St. Louis, MO
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418
mi
from
St. Louis, MO
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1112
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from
Tampa, FL
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Washington, District of Columbia 20009
1127
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from
Washington,
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1305
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from
Wilton Manors, FL
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1405
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from
Worcester, MA
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