Safety and Effectiveness of Belimumab in Systemic Lupus Erythematosus Registry



Status:Recruiting
Conditions:Lupus
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:7/18/2018
Start Date:February 21, 2013
End Date:January 31, 2025
Contact:US GSK Clinical Trials Call Center
Email:GSKClinicalSupportHD@gsk.com
Phone:877-379-3718

Use our guide to learn which trials are right for you!

A 5-Year Prospective Observational Registry to Assess Adverse Events of Interest and Effectiveness in Adults With Active, Autoantibody-Positive Systemic Lupus Erythematosus Treated With or Without BENLYSTA™ (Belimumab)

The purpose of this registry is to collect additional information regarding the side effects
and effectiveness of BENLYSTA (belimumab) when given with other lupus medicines to adults
with active systemic lupus erythematosus (SLE). Information will be collected on serious
events that are not that common or may only be seen with long-term treatment. These events
include death, cancers, serious infections and other infections of interest, and serious
mental health problems. Information on the effectiveness of BENLYSTA will also be collected.

The registry will enroll 2 groups of patients. One group will include patients who are
currently taking lupus medicines along with BENLYSTA (With BENLYSTA). The other group will
include patients who are taking lupus medicines but do not take BENLYSTA (Without BENLYSTA).
For every 3 participants enrolled in the registry, 2 will be taking BENLYSTA and 1 will not.
After enrollment, changes in lupus medications, including starting or stopping BENLYSTA, are
at the discretion of the physician, and all patients will continue to be followed regardless
of changes in their lupus medicines until study completion. Physicians will manage the
patient in accordance with their medical judgment and standard of care. Data will be
collected at enrollment and at 6 month intervals for 5 years.

Key Inclusion Criteria:

- Clinical diagnosis of active SLE.

- Autoantibody-positive.

- Current SLE treatment includes BENLYSTA and/or immunosuppressants (for example,
azathioprine, methotrexate, cyclophosphamide, mycophenolate, and biologics).

Key Exclusion Criteria:

- Have received treatment with an investigational agent within the past year.

- Are currently enrolled in a placebo-controlled BENLYSTA (belimumab) clinical trial or
a continuation trial in which belimumab is used as an investigational agent.

- Have a history of BENLYSTA exposure, but are not currently receiving BENLYSTA.

- Current SLE treatment includes only an antimalarial (for example, hydroxychloroquine)
or only steroids.
We found this trial at
109
sites
Springfield, Massachusetts 01199
Phone: 877-379-3718
?
mi
from
Springfield, MA
Click here to add this to my saved trials
Ann Arbor, Michigan 48109
Phone: 877-379-3718
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
Arlington, Virginia 22205
Phone: 877-379-3718
?
mi
from
Arlington, VA
Click here to add this to my saved trials
Atlanta, Georgia 30341
Phone: 877-379-3718
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Austin, Texas 78705
?
mi
from
Austin, TX
Click here to add this to my saved trials
Bakersfield, California 93309
Phone: 877-379-3718
?
mi
from
Bakersfield, CA
Click here to add this to my saved trials
Baltimore, Maryland 21201
Phone: 877-379-3718
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Baton Rouge, Louisiana 70809
Phone: 877-379-3718
?
mi
from
Baton Rouge, LA
Click here to add this to my saved trials
Birmingham, Alabama 35249
Phone: 877-379-3718
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Bronx, New York 10461
Phone: 877-379-3718
?
mi
from
Bronx, NY
Click here to add this to my saved trials
Camden, New Jersey 08103
Phone: 877-379-3718
?
mi
from
Camden, NJ
Click here to add this to my saved trials
Charleston, South Carolina 29425
Phone: 877-379-3718
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Charleston, South Carolina 29425
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Charlotte, North Carolina 28203
Phone: 877-379-3718
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
Charlotte, North Carolina 28203
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
Charlotte, North Carolina 28203
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
Chicago, Illinois 60611
Phone: 877-379-3718
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Chicago, Illinois 60611
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Clearwater, Florida 33759
Phone: 877-379-3718
?
mi
from
Clearwater, FL
Click here to add this to my saved trials
Columbia, South Carolina 29203
?
mi
from
Columbia, SC
Click here to add this to my saved trials
Columbus, Ohio 43219
Phone: 877-379-3718
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Covina, California 91723
?
mi
from
Covina, CA
Click here to add this to my saved trials
Culver City, California 90232
?
mi
from
Culver City, CA
Click here to add this to my saved trials
Danbury, Connecticut 06810
Phone: 877-379-3718
?
mi
from
Danbury, CT
Click here to add this to my saved trials
Danville, Virginia 24541
Phone: 877-379-3718
?
mi
from
Danville, VA
Click here to add this to my saved trials
Detroit, Michigan 48202
Phone: 877-379-3718
?
mi
from
Detroit, MI
Click here to add this to my saved trials
Duncansville, Pennsylvania 16635
Phone: 877-379-3718
?
mi
from
Duncansville, PA
Click here to add this to my saved trials
Eagan, Minnesota 55121
Phone: 877-379-3718
?
mi
from
Eagan, MN
Click here to add this to my saved trials
Edina, Minnesota 55435
Phone: 877-379-3718
?
mi
from
Edina, MN
Click here to add this to my saved trials
Edmond, Oklahoma 73013
Phone: 877-379-3718
?
mi
from
Edmond, OK
Click here to add this to my saved trials
Fort Lauderdale, Florida 33308
Phone: 877-379-3718
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
Gainesville, Georgia 30501
Phone: 877-379-3718
?
mi
from
Gainesville, GA
Click here to add this to my saved trials
Glendale, Arizona 85304
Phone: 877-379-3718
?
mi
from
Glendale, AZ
Click here to add this to my saved trials
Glendale, California 91204
Phone: 877-379-3718
?
mi
from
Glendale, CA
Click here to add this to my saved trials
Goodyear, Arizona 85338
?
mi
from
Goodyear, AZ
Click here to add this to my saved trials
Hamden, Connecticut 06518
Phone: 877-379-3718
?
mi
from
Hamden, CT
Click here to add this to my saved trials
Henderson, Nevada 89052
Phone: 877-379-3718
?
mi
from
Henderson, NV
Click here to add this to my saved trials
Hixson, Tennessee 37343
Phone: 877-379-3718
?
mi
from
Hixson, TN
Click here to add this to my saved trials
Homestead, Florida 33030
?
mi
from
Homestead, FL
Click here to add this to my saved trials
Houston, Texas 77030
Phone: 877-379-3718
?
mi
from
Houston, TX
Click here to add this to my saved trials
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Jackson, Mississippi 39202
Phone: 877-379-3718
?
mi
from
Jackson, MS
Click here to add this to my saved trials
Juniper, Florida 33458
Phone: 877-379-3718
?
mi
from
Juniper, FL
Click here to add this to my saved trials
La Mesa, California 91942
Phone: 877-379-3718
?
mi
from
La Mesa, CA
Click here to add this to my saved trials
Lake Charles, Louisiana 70601
?
mi
from
Lake Charles, LA
Click here to add this to my saved trials
Lakewood, California 90712
Phone: 877-379-3718
?
mi
from
Lakewood, CA
Click here to add this to my saved trials
Lansing, Michigan 48917
Phone: 877-379-3718
?
mi
from
Lansing, MI
Click here to add this to my saved trials
Largo, Florida 33770
Phone: 877-379-3718
?
mi
from
Largo, FL
Click here to add this to my saved trials
Lexington, Kentucky 40504
?
mi
from
Lexington, KY
Click here to add this to my saved trials
Loma Linda, California 92357
Phone: 877-379-3718
?
mi
from
Loma Linda, CA
Click here to add this to my saved trials
Los Angeles, California 90025
Phone: 877-379-3718
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Los Angeles, California 90025
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Los Angeles, California 90025
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Manhasset, New York 11030
Phone: 877-379-3718
?
mi
from
Manhasset, NY
Click here to add this to my saved trials
Manitowoc, Wisconsin 54221
Phone: 877-379-3718
?
mi
from
Manitowoc, WI
Click here to add this to my saved trials
Marietta, Georgia 30060
?
mi
from
Marietta, GA
Click here to add this to my saved trials
Meridian, Idaho 83642
Phone: 877-379-3718
?
mi
from
Meridian, ID
Click here to add this to my saved trials
Miami, Florida 33136
Phone: 877-379-3718
?
mi
from
Miami, FL
Click here to add this to my saved trials
Miami, Florida 33136
?
mi
from
Miami, FL
Click here to add this to my saved trials
Miami, Florida 33136
?
mi
from
Miami, FL
Click here to add this to my saved trials
Mineola, New York 11501
Phone: 877-379-3718
?
mi
from
Mineola, NY
Click here to add this to my saved trials
Morton Grove, Illinois 60053
Phone: 877-379-3718
?
mi
from
Morton Grove, IL
Click here to add this to my saved trials
Murrieta, California 92563
Phone: 877-379-3718
?
mi
from
Murrieta, CA
Click here to add this to my saved trials
Nashville, Tennessee 37203
Phone: 877-379-3718
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Nassau Bay, Texas 77058
Phone: 877-379-3718
?
mi
from
Nassau Bay, TX
Click here to add this to my saved trials
New Bern, North Carolina 28562
Phone: 877-379-3718
?
mi
from
New Bern, NC
Click here to add this to my saved trials
New Brunswick, New Jersey 08901
Phone: 877-379-3718
?
mi
from
New Brunswick, NJ
Click here to add this to my saved trials
New York, New York 10032
Phone: 877-379-3718
?
mi
from
New York, NY
Click here to add this to my saved trials
New York, New York 10032
?
mi
from
New York, NY
Click here to add this to my saved trials
Norfolk, Virginia 23502
Phone: 877-379-3718
?
mi
from
Norfolk, VA
Click here to add this to my saved trials
North Miami Beach, Florida 33179
?
mi
from
North Miami Beach, FL
Click here to add this to my saved trials
Oklahoma City, Oklahoma 73112
Phone: 877-379-3718
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Oklahoma City, Oklahoma 73112
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Omaha, Nebraska 68131
Phone: 877-379-3718
?
mi
from
Omaha, NE
Click here to add this to my saved trials
Palm Harbor, Florida 34684
Phone: 877-379-3718
?
mi
from
Palm Harbor, FL
Click here to add this to my saved trials
Parana, Entre Ríos
Phone: 877-379-3718
?
mi
from
Parana,
Click here to add this to my saved trials
Pembroke Pines, Florida 33028
Phone: 877-379-3718
?
mi
from
Pembroke Pines, FL
Click here to add this to my saved trials
Pensacola, Florida 32503
Phone: 877-379-3718
?
mi
from
Pensacola, FL
Click here to add this to my saved trials
Perrysburg, Ohio 43551
?
mi
from
Perrysburg, OH
Click here to add this to my saved trials
Phoenix, Arizona 85012
Phone: 877-379-3718
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Phoenix, Arizona 85012
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Pittsburgh, Pennsylvania 15213
Phone: 877-379-3718
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
Plano, Texas 75093
?
mi
from
Plano, TX
Click here to add this to my saved trials
Plantation, Florida 33324
Phone: 877-379-3718
?
mi
from
Plantation, FL
Click here to add this to my saved trials
Pomona, California 91767
Phone: 877-379-3718
?
mi
from
Pomona, CA
Click here to add this to my saved trials
Raleigh, North Carolina 27614
Phone: 877-379-3718
?
mi
from
Raleigh, NC
Click here to add this to my saved trials
Roanoke, Virginia 24013
Phone: 877-379-3718
?
mi
from
Roanoke, VA
Click here to add this to my saved trials
Rocky Mount, North Carolina 27804
?
mi
from
Rocky Mount, NC
Click here to add this to my saved trials
Roslyn, New York 11576
Phone: 877-379-3718
?
mi
from
Roslyn, NY
Click here to add this to my saved trials
Round Rock, Texas 78681
Phone: 877-379-3718
?
mi
from
Round Rock, TX
Click here to add this to my saved trials
Saint Louis, Missouri 63110
Phone: 877-379-3718
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
San Diego, California 92111
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Seattle, Washington 98109
Phone: 877-379-3718
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Shreveport, Louisiana 71103
Phone: 877-379-3718
?
mi
from
Shreveport, LA
Click here to add this to my saved trials
Smithtown, New York 11787
Phone: 877-379-3718
?
mi
from
Smithtown, NY
Click here to add this to my saved trials
South Bend, Indiana 46601
Phone: 877-379-3718
?
mi
from
South Bend, IN
Click here to add this to my saved trials
Summit, New Jersey 07901
Phone: 877-379-3718
?
mi
from
Summit, NJ
Click here to add this to my saved trials
Teaneck, New Jersey 07666
Phone: 877-379-3718
?
mi
from
Teaneck, NJ
Click here to add this to my saved trials
Thousand Oaks, California 91360
?
mi
from
Thousand Oaks, CA
Click here to add this to my saved trials
Toledo, Ohio 43608
Phone: 877-379-3718
?
mi
from
Toledo, OH
Click here to add this to my saved trials