Bladder ARFI (Acoustic Radiation Force Impulse) Study



Status:Completed
Healthy:No
Age Range:Any - 18
Updated:1/5/2018
Start Date:October 2012
End Date:October 2016

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Evaluation of Pediatric Urinary Bladder Wall Thickening and Fibrosis Using Acoustic Radiation Force Impulse (ARFI)-Derived Shear Wave Velocities

Urinary bladder fibrosis (thickening and scarring) is fairly uncommon in children.
Traditionally, the presence of urinary bladder fibrosis has been confirmed directly with
bladder biopsy or using urodynamic testing. In this study we will use ultrasound scanning and
ARFI (acoustic radiation force impulse) wave velocities to potentially identify any urinary
bladder wall fibrosis.

Urinary bladder fibrosis (thickening and scarring) is fairly uncommon in children.
Traditionally, the presence of urinary bladder fibrosis has been confirmed directly with
bladder biopsy or using urodynamic testing.

We will use ultrasound ARFI (acoustic radiation force impulse)-derived shear wave velocities
to potentially identify the presence of urinary bladder wall fibrosis. We hypothesize that
shear wave velocities found within the bladder wall will increase with increasing evidence of
fibrosis.

Inclusion Criteria:

1. 18 years of age or younger

2. Have an order for urodynamic testing from your doctor

Exclusion Criteria:

1. Adults

2. Unwilling to sign consent form
We found this trial at
1
site
Ann Arbor, Michigan 48109
Principal Investigator: Ethan Smith, M.D.
Phone: 734-232-9245
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mi
from
Ann Arbor, MI
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