Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository



Status:Completed
Conditions:Healthy Studies
Therapuetic Areas:Other
Healthy:No
Age Range:30 - Any
Updated:2/2/2019
Start Date:May 2012
End Date:August 28, 2018

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The purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional
Review Board Pro00011196) to specifically target and enroll 1,000 participants across age
groups and other demographic categories in order to develop a diverse cohort with specific
physical and cognitive performance data paired with biological samples.

The MURDOCK Study, proposes this Horizon 2 study to collect a brief physical and cognitive
performance assessment from 1,000 MURDOCK Registry participants. Blood sample aliquots will
also be obtained. These physical and cognitive performance data, paired with -omics data from
plasma and serum sample analyses, offer promise in the discovery of biomarkers for functional
decline. This research will provide an important basis for our understanding of the physical,
lifestyle, and genetic factors which, over the lifespan, contribute to changes in physical
and cognitive capabilities as we age.

Inclusion Criteria:

- A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions)
or certain portions of Rowan, Mecklenburg, or Stanly counties in North Carolina for 6
or more months of the year.

- Age 30 or older

Exclusion Criteria:

- Female that is currently pregnant

- Having had a heart attack, angina, congestive heart failure, or fluid in the lungs
within the past 6 months

- Participant that requires consent by a legally authorized representative

- Participant that cannot walk 30ft without human assistance
We found this trial at
6
sites
Harrisburg, North Carolina 28075
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Harrisburg, NC
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Charlotte, North Carolina 28262
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Charlotte, NC
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Concord, North Carolina 28025
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Concord, NC
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Concord, NC
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Davidson, North Carolina 28036
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Davidson, NC
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Huntersville, North Carolina 28078
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Huntersville, NC
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