A Study to Evaluate Safety and Efficacy of TTP054 for 12 Weeks in Subjects With Type 2 Diabetes

Inclusion Criteria:

- Diagnosis of type 2 diabetes mellitus

- On a stable (for the last 3 months) regimen of either metformin alone or metformin in
combination with one additional acceptable oral antidiabetic (OAD) agent

- HbA1c: Metformin only: 7.0 - 11.0%; Metformin + acceptable OAD agent: 6.5 - 9.5%

Exclusion Criteria:

- History or evidence of significant diabetic complications

- History of heart attack, stroke or congestive heart failure

- Severe, uncontrolled hypertension

- Frequent hypoglycemia

- Women of child-bearing potential