Anti-caries Potential of a Sodium Monofluorophosphate and Calcium Sodium Phosphosilicate Dentifrice
| Status: | Completed |
|---|---|
| Conditions: | Dental |
| Therapuetic Areas: | Dental / Maxillofacial Surgery |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 7/16/2013 |
| Start Date: | May 2012 |
| End Date: | June 2013 |
| Contact: | US GSK Clinical Trials Call Center |
| Email: | GSKClinicalSupportHD@gsk.com |
| Phone: | 877-379-3718 |
In Situ Study to Confirm the Anti-caries Potential of a 1.1365% w/w Sodium Monofluorophosphate (1500ppm F) Dentifrice
In situ study to compare treatment effect on enamel remineralization potential, measured by
surface microhardness recovery (SMHR) and Enamel Fluoride Uptake (EFU). The study will
explore the efficacy of an experimental sodium monofluorophosphate (SMFP) dentifrice
containing calcium sodium phosphosilicate (CSP) in comparison to an experimental SMFP only
dentifrice.
Inclusion Criteria:
- Wears a removable bilateral mandibular partial denture that has good stability and
support, with sufficient room on each side in the posterior buccal flange area to
accommodate two enamel specimens [required dimensions 12 x 7 millimeters (mm)].
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