Ad Hoc Percutaneous Coronary Intervention Study in Acute Coronary Syndrome Patients



Status:Completed
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 127
Updated:4/21/2016
Start Date:July 2012
End Date:June 2014

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A Randomized, Open-label Study to Compare the Platelet Inhibition With VerifyNow Assay of Ticagrelor Versus Clopidogrel in Troponin Negative Acute Coronary Syndrome Subjects Undergoing Ad Hoc Percutaneous Coronary Intervention

The purpose of this study is to assess the pharmacodynamic effect of ticagrelor in ACS
patients undergoing an Ad Hoc PCI

A randomized, open-label, multiple-center, parallel group study to compare the platelet
inhibition with VerifyNow assay of ticagrelor versus clopidogrel in troponin negative Acute
Coronary Syndrome (ACS) subjects undergoing Ad Hoc percutaneous coronary intervention (PCI)

Inclusion Criteria:

- Provision of signed and dated informed consent before initiation of any study-related
procedures

- Male or female patients aged 18 years or older

- Documented acute coronary syndrome and troponin negative and undergoing Ad Hoc
percutaneous coronary intervention (PCI)

- Females must be post menopausal or surgically sterile

- Taking aspirin as an anti-platelet medication

Exclusion Criteria:

- Use of any thienopyridine or ticagrelor within 7 days prior to randomization

- Any indication for oral anticoagulant (e.g., atrial fibrillation, mitral stenosis or
prosthetic heart valve)

- Contraindication that ticagrelor or clopidogrel should not be administered Patient
requires dialysis

- History of intolerance or allergy to aspirin
We found this trial at
18
sites
1164
mi
from 91732
Oklahoma City, OK
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2424
mi
from 91732
Belleville, NJ
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1784
mi
from 91732
Birmingham, AL
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2436
mi
from 91732
Bronx, NY
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1880
mi
from 91732
Cincinnati, OH
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Greensboro, North Carolina 27401
2152
mi
from 91732
Greensboro, NC
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2127
mi
from 91732
Jacksonville, FL
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1511
mi
from 91732
Minneapolis, MN
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1511
mi
from 91732
Minneapolis, MN
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2435
mi
from 91732
New York, NY
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2435
mi
from 91732
New York, NY
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1341
mi
from 91732
North Kansas, MO
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2267
mi
from 91732
Richmond, VA
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355
mi
from 91732
San Francisco, CA
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1666
mi
from 91732
Tupelo, MS
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1315
mi
from 91732
Tyler, TX
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2281
mi
from 91732
Washington,
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1936
mi
from 91732
Ypsilanti, MI
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