Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology
| Status: | Archived |
|---|---|
| Conditions: | Colitis, Neurology, Gastrointestinal, Pulmonary |
| Therapuetic Areas: | Gastroenterology, Neurology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
Genomics, SNPs, and Clinical Neonatology
This research seeks to establish a neonatal DNA Tissue Bank to find out if differences in
small segments of DNA predispose babies to Chronic Lung Disease (CLD), Periventricular Brain
Injury (PVI), Necrotizing Enterocolitis (NEC), or Hypoxic Respiratory Failure (HRF).
This genetic predisposition study does not involve investigational drugs, devices, or
treatments. Our broad goal is to identify genomic factors, which contribute to the
development or exacerbation of common and critical illnesses that affect preterm and
near-term infants. We seek to accomplish this goal in the following ways:
- First: to test candidate gene DNA variations and link already identified single
nucleotide polymorphisms (SNPs) producing functional alterations to the risk of
clinically important disorders.
- Second: to utilize a whole-genomic approach to identify SNPs not previously linked to
the risk of development or progression of neonatal disorders.
We found this trial at
2
sites
Children's Mercy Hospital Children's Mercy Hospitals and Clinics continues redefining pediatric medicine throughout the Midwest...
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Truman Medical Center Located in the heart of downtown Kansas City, TMC Hospital Hill is...
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