Chronology of Occult and Gross Coagulopathy in Burn Patients
| Status: | Recruiting |
|---|---|
| Conditions: | Hospital, Hematology |
| Therapuetic Areas: | Hematology, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 7/15/2016 |
| Start Date: | July 2012 |
| End Date: | June 2017 |
| Contact: | Melissa McLawhorn |
| Email: | melissa.m.mclawhorn@medstar.net |
| Phone: | 202-877-6181 |
Determining the Chronology of Occult and Gross Coagulopathy in Thermally Injured Patients: A Systems Biology Approach
The purpose of the study is to identify the inflammatory and coagulation pathways and
mechanisms that are activated immediately following burn injury, and how they affect
outcomes in terms of organ failure and death. This study also addresses the limitation of
current tests (PT, PTT, and platelet counts) employed to identify coagulation disturbances
in severely injured patients both in a comprehensive and rapid manner.
mechanisms that are activated immediately following burn injury, and how they affect
outcomes in terms of organ failure and death. This study also addresses the limitation of
current tests (PT, PTT, and platelet counts) employed to identify coagulation disturbances
in severely injured patients both in a comprehensive and rapid manner.
Inclusion Criteria:
- Patients, male or female, > or = 18 years of age, who arrive at Burn/Trauma Center
with anticipated admission to The Burn Center within 4 hours of injury, with a
thermal burn injury due to flash, flame, contact with hot object or liquid.
Exclusion Criteria:
- Patients suffering concomitant trauma that are in hemorrhagic shock. Patients with a
preexisting history of coagulopathy, or currently taking anti-coagulants. Children
and pregnant women. Patients with chemical or electrical injury. Patients who do not
fluently speak either English or Spanish.
We found this trial at
1
site
Washington, District of Columbia
Principal Investigator: Jeffrey Shupp, MD
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