Comparison of Muscle Atrophy After Direct Anterior & Posterior Total Hip Arthroplasty



Status:Active, not recruiting
Conditions:Arthritis, Osteoarthritis (OA), Neurology
Therapuetic Areas:Neurology, Rheumatology
Healthy:No
Age Range:18 - 75
Updated:3/22/2019
Start Date:May 2012
End Date:July 2019

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The Influence of Operative Approach on Muscle Atrophy After Total Hip Arthroplasty: A Comparison of Anterior and Posterior Approaches

This project is designed to use MRI to evaluate pre- and post-arthroplasty hips; the specific
aims of this project are three-fold. First, the investigators intend to compare the amount of
muscle atrophy and tendon damage that occurs around the hip between two commonly-used
operative approaches: the direct-anterior approach and the posterior approach. Second, the
investigators aim to provide baseline data on the amount of muscle atrophy and tendon damage
that should reasonably be expected to occur with both of these approaches. Third, the
investigators will document the degree of recovery of the periprosthetic soft tissues
post-surgery in both patient groups.

The investigators first hypothesis is that the posterior approach will demonstrate
significantly more damage to the abductors, piriformis, and short external rotators than the
direct anterior approach, which will demonstrate minimal soft tissue damage. The
investigators second hypothesis is that both surgical approaches will cause some degree of
baseline muscle damage and atrophy, in a predictable pattern. The investigators third
hypothesis is that each of the surgical approaches inherently cause some degree of soft
tissue damage, and that the periprosthetic soft tissues that are incised during the surgical
exposure will recover in a predictable pattern which is consistent but unique within each
group


Inclusion Criteria:

1. Patients undergoing elective, primary total hip arthroplasty

2. Use of Cementless Total Hip components

3. Preoperative diagnosis of degenerative joint disease secondary to osteoarthritis

Exclusion Criteria:

1. Prior surgery on the affected hip

2. No implanted medical devices or metallic debris in the patient which will preclude use
of MRI

3. patients must be able to participate in standard post-arthroplasty rehabilitation
protocols.
We found this trial at
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New York, New York 10075
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