Long Term Effects On Recipients of Hematopoietic Stem Cell Transplantation

Primary Objective: Implement long-term follow-up guidelines for children, adolescents and
young adults who are survivors of HSCT while establishing a database which captures the
survivor's lifetime care.

Secondary Objectives:

- Collect evidence-based data through a structured framework of periodic physical
examination, laboratory and medical tests to monitor late effects in our HSCT survivors.

- Establish standards of care for late effects of therapy post HSCT for malignant and
non-malignant diagnoses.

- Provide early identification and intervention towards recognized problems, as well as
consistent education to foster a healthy lifestyle to all survivors.

- Collect blood and tissue samples to study immune reconstitution of all immune cell types
and learn more about immune reconstitution and its affect on post-HSCT complications and
disease free survival.

Inclusion Criteria:

- Participant is scheduled to receive OR has received a hematopoietic stem cell
transplant (HSCT) for any condition.

- Participant may have had a HSCT in another institution than Lucile Packard Children's
Hospital (LPCH) yet has transferred follow-up long-term care to our institution and is
being seen through the late-effects clinic from the Pediatric HSCT program.

- Participant AND/OR parent/legally authorized representative is able to provide written
informed consent and assent (as applicable) for participation.

Exclusion Criteria:

- Participant has relapsed from a malignant diagnosis post HSCT and is not being
worked-up for a new HSCT.

- Participant or patient's authorized guardian is unable to provide consent and assent