Genetic Influence on Statin Pharmacodynamics
| Status: | Withdrawn |
|---|---|
| Conditions: | High Cholesterol |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | March 2012 |
| End Date: | March 2022 |
An Observational Study Investigating Genetic Influences on Clinical Outcomes and Change in Carotid Intimal Thickness in Adults Taking Atorvastatin, Simvastatin, or Lovastatin
The study intends to investigate whether genetics influence how individuals respond to
statins (clinical outcomes and changes in carotid intimal media thickness)
statins (clinical outcomes and changes in carotid intimal media thickness)
Inclusion Criteria:
- recently (within past 3 months) started taking atorvastatin, lovastatin, or
simvastatin
Exclusion Criteria:
- concomitant uses of medications, supplements, or OTCs known to interfere with statin
metabolism
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