Deep Brain Stimulation for the Treatment of Alzheimer's Disease

Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Age Range:45 - 85
Start Date:March 2012
End Date:January 2018
Contact:Carson Reider, PhD

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Deep Brain Stimulation (DBS) for Treatment of the Cognitive, Behavioral, and Functional Disability of Alzheimer's Disease

The purpose of this clinical study is to investigate the safety and efficacy of deep brain
stimulation (DBS)as a treatment option for patients with cognitive, behavioral, and
functional disability of Alzheimer's disease.

Inclusion Criteria:

- Diagnosis of probable AD according to the National Institute of Neurological and
Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders
Association (NINCDS-ADRDA) criteria

Exclusion Criteria:

- Has significant neurological disease, other than Alzheimer's disease, e.g., multiple
sclerosis, Parkinson's disease and ischemic stroke, or severe brain atrophy or the
presence of subdural hygromas or subdural hematomas.

- Evidence of substance abuse (alcohol or other drug) abuse or dependence during the
previous 12 months (DSM-IV Criteria).
We found this trial at
Columbus, Ohio 43210
Principal Investigator: Ali Rezai, MD
Phone: 614-293-9274
Columbus, OH
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