Effect of Laser Use on Guided Tissue Regeneration in Treatment of Molar Teeth With Class 2 Furcation Affected by Periodontitis
| Status: | Completed |
|---|---|
| Conditions: | Dental |
| Therapuetic Areas: | Dental / Maxillofacial Surgery |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 5/5/2014 |
| Start Date: | December 2011 |
| End Date: | June 2013 |
| Contact: | Rosemary Thomas, DMD |
| Email: | rosemary.thomas@uth.tmc.edu |
| Phone: | 832-640-1753 |
Treatment of Class II Furcation Defects in the Maxillary and Mandibular Molars With Bioresorbable Collagen Membrane and Laser
Purpose: The proposed study will evaluate and compare the clinical response of using
bioresorbable collagen membrane alone or defect debridement with erbium Laser irradiation
in conjunction with bioresorbable collagen membrane in the treatment of Class II furcation
defects in maxillary and mandibular teeth. The study will examine whether there is a
superior regeneration potential when the laser energy is combined with membrane defect
isolation.
Procedure: The study will use 2 groups, a control group and a test group with 16 patients in
each group, with severe chronic periodontitis having clinical or radiographic evidence of
Class II furcation defects in the buccal or lingual of the mandibular molars or Class II
furcation defects on the buccal of maxillary molars. 16 patients will serve as the control
group and open flap debridement with bioresorbable collagen membrane will be the mode of
treatment. Group 2: 16 patients will serve as the test group and will undergo open flap
debridement in conjunction with Er, Cr: YSGG laser irradiation and a bioresorbable collagen
membrane will be used.
bioresorbable collagen membrane alone or defect debridement with erbium Laser irradiation
in conjunction with bioresorbable collagen membrane in the treatment of Class II furcation
defects in maxillary and mandibular teeth. The study will examine whether there is a
superior regeneration potential when the laser energy is combined with membrane defect
isolation.
Procedure: The study will use 2 groups, a control group and a test group with 16 patients in
each group, with severe chronic periodontitis having clinical or radiographic evidence of
Class II furcation defects in the buccal or lingual of the mandibular molars or Class II
furcation defects on the buccal of maxillary molars. 16 patients will serve as the control
group and open flap debridement with bioresorbable collagen membrane will be the mode of
treatment. Group 2: 16 patients will serve as the test group and will undergo open flap
debridement in conjunction with Er, Cr: YSGG laser irradiation and a bioresorbable collagen
membrane will be used.
All subjects will be patients of record in the Graduate Periodontics clinic at the UT School
of Dentistry. These individuals will have already been diagnosed with chronic periodontitis
and require surgical intervention to treat the disease process. All patients will have
received initial periodontal therapy consisting of oral hygiene instructions and scaling and
root planing. Once enrolled in the study, all subjects will receive surgical therapy
involving opened flap debridement of the affected furcation defects along with membrane
isolation of the defect. The test group will have debridement performed with the Er,Cr:YSGG
laser and ultrasonic cleansing, while the control group will have hand instrumentation along
with ultrasonic cleansing. This procedure will take approximately 1.5 hours. Postoperative
appointments at 1,2,4,8 weeks requiring 15-30 minutes per appointment; at 3 months for
periodontal maintenance and reinforcement of home care requiring 45 minutes; and at 6 months
for periodontal maintenance, reassessment of the furcation defect and correction of residual
defects requiring 75 minutes. Patients will be exited from the study 2 weeks after the last
maintenance appointment and placed on recall with the Department of Periodontics dental
hygienist. The total time commitment for each patient is 6 months.
of Dentistry. These individuals will have already been diagnosed with chronic periodontitis
and require surgical intervention to treat the disease process. All patients will have
received initial periodontal therapy consisting of oral hygiene instructions and scaling and
root planing. Once enrolled in the study, all subjects will receive surgical therapy
involving opened flap debridement of the affected furcation defects along with membrane
isolation of the defect. The test group will have debridement performed with the Er,Cr:YSGG
laser and ultrasonic cleansing, while the control group will have hand instrumentation along
with ultrasonic cleansing. This procedure will take approximately 1.5 hours. Postoperative
appointments at 1,2,4,8 weeks requiring 15-30 minutes per appointment; at 3 months for
periodontal maintenance and reinforcement of home care requiring 45 minutes; and at 6 months
for periodontal maintenance, reassessment of the furcation defect and correction of residual
defects requiring 75 minutes. Patients will be exited from the study 2 weeks after the last
maintenance appointment and placed on recall with the Department of Periodontics dental
hygienist. The total time commitment for each patient is 6 months.
Inclusion Criteria:
- should be 18 years of age in good general health
- should exhibit an O'Leary plaque score of 20% or less after initial therapy
- class II furcations defects should be present in the buccal of the maxillary molars
or buccal or lingual of the mandibular molars
- tooth mobility should not exceed Miller Class II
Exclusion Criteria:
- patients who will be excluded include those with known hypersensitivity or allergy to
chlorhexidine,
- uncontrolled diabetics,
- patients who are immunocompromised,
- who have taken steroids within 6 months of study enrollment,
- individuals who are pregnant and heavy smokers (> 10 cigarettes/day)
We found this trial at
1
site
Houston, Texas 77030
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