Behavioral Effects of Pregabalin and Cannabis

Therapuetic Areas:Psychiatry / Psychology
Age Range:18 - 50
Start Date:February 1, 2017
End Date:December 31, 2019

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Behavioral Effects of Drugs (Outpatient)(43)

Cannabis is the most commonly used illicit drug in the United States, and its use is
associated with rates of development of abuse and dependence, treatment admission and relapse
that are comparable to other illicit drugs. Currently there is no effective pharmacological
treatment for cannabis-use disorders. The purpose of the present study is to evaluate the
ability of pregabalin to reduce cannabis use thereby evaluating its effectiveness as a
medication for cannabis-use disorders.

Inclusion Criteria:

- regular cannabis use

- good health other than cannabis use

- willingness to attempt abstinence

- effective form of birth control in female subjects

- available for up to 6 hrs every day for two 2-week test periods with an intervening
break of 10 days each

- located in close proximity to University of Kentucky

Exclusion Criteria:

- medical screening outcomes outside normal ranges or deemed clinical insignificant

- medical history that would contraindicate pregabalin administration
We found this trial at
Lexington, Kentucky 40536
Principal Investigator: Joshua A. Lile, Ph.D.
Phone: 859-257-5388
Lexington, KY
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