Screening Study of Patient Eligibility for Participation in National Cancer Institute Radiation Therapy Clinical Trials

OBJECTIVES:

- Evaluate patient eligibility for participation in NCI Radiation Oncology Branch
protocols.

- Permit standard therapy for patients ineligible for active Radiation Oncology Branch
protocols who present a novel or unique clinical training opportunity or who present
conditions requiring immediate intervention in order to avoid compromising patient's
health.

OUTLINE: Patients undergo various diagnostic procedures and clinical testing to determine
protocol eligibility. The testing and procedures may include hepatitis screen; HIV serology;
MRI, CT, and PET scans; pulmonary function tests; arteriogram; tumor biopsy; and
laparoscopy.

PROJECTED ACCRUAL: A total of 1,000 patients will be accrued for this study within 5 years.