Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer



Status:Completed
Conditions:Lung Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:6/28/2017
Start Date:March 2012

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Molecular Characterization of Lung Cancer: A Collaboration With the Cancer Genome Atlas Project (TGCA)

RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help
doctors learn more about changes that occur in DNA and identify biomarkers related to
cancer.

PURPOSE: This research trial studies tissue samples from patients with non-small cell lung
cancer.

OBJECTIVES:

- To identify and characterize single nucleotide variations (SNVs) in non-small cell lung
cancer (NSCLC) specimens.

- To identify and characterize structural variations in the genomes of NSCLC specimens.

- To identify and characterize other genomic alterations including, but not limited to,
expression profiling and methylation.

OUTLINE: DNA and RNA extracted from archived specimens are analyzed for single nucleotide
variations, structural variations in the genomes, and other genomic alterations including,
but not limited to, gene expression profiling and methylation. Clinical data related to
disease, treatment, and recurrence from each patient sample is also collected.

- Patient must have been registered to CALGB 140202.

- Tumor histology should be either primary adenocarcinoma or squamous cell carcinoma of
the lung.

- Patients are eligible for this study if their samples from CALGB 140202 are
available.

- All living patients must sign the CALGB 151107 consent form to be eligible for this
trial.
We found this trial at
11
sites
42 E Laurel Rd # 2545
Voorhees, New Jersey 08043
(800) 826-6737
Phone: 856-325-6757
Cancer Institute of New Jersey at Cooper - Voorhees Cooper University Health Care, the clinical...
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Voorhees, NJ
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666 Elm Street
Buffalo, New York 14263
(716) 845-2300
Phone: 877-275-7724
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
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Buffalo, NY
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902 Savannah Road
Lewes, Delaware 19958
(302) 645-3770
Phone: 302-645-3171
Tunnell Cancer Center at Beebe Medical Center The Robert & Eolyne Tunnell Cancer Center at...
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Lewes, DE
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593 Eddy Street
Providence, Rhode Island 02903
401-444-4000
Phone: 401-444-1488
Rhode Island Hospital Comprehensive Cancer Center The Comprehensive Cancer Center at Rhode Island Hospital is...
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Providence, RI
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Baltimore, Maryland 21201
Phone: 800-888-8823
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Baltimore, MD
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20 Duke Clinic Cir
Durham, North Carolina 27710
(888) 275-3853
Phone: 888-275-3853
Duke Cancer Institute Leading-edge cancer care and research have been a hallmark of Duke Medicine...
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Durham, NC
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Elkton, Maryland 21921
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Elkton, MD
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8700 Beverly Blvd.
Los Angeles, California 90048
1-800-233-2771
Phone: 310-652-0530
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center Cedars-Sinai's Samuel Oschin Comprehensive Cancer Institute...
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Los Angeles, CA
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4701 Ogletown-Stanton Road
Newark, Delaware 19713
302-623-4450
CCOP - Christiana Care Health Services Christiana Care's Cancer Research Program is part of a...
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Newark, DE
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164 Summit Ave
Providence, Rhode Island 02906
(401) 793-2500
Phone: 401-793-2224
Miriam Hospital The Miriam Hospital is a private, not-for-profit hospital, with a history of providing...
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Providence, RI
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Saint Louis, Missouri 63110
Phone: 314-362-4819
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Saint Louis, MO
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