Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Due to Burn Injury

Conditions:Chronic Pain, Hospital
Therapuetic Areas:Musculoskeletal, Other
Age Range:18 - 64
Start Date:June 2011
Contact:Felipe Fregni, MD

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Cortical Modulation With Transcranial Direct Current Stimulation (tDCS) for Neuropathic Symptoms Following Burn Injury.

The purpose of this study is to investigate the effects of transcranial direct current
stimulation (tDCS) on the neuropathic symptoms (pain/itch) due to a burn injury. The
investigators hypothesize that the active tDCS group will show a significant pain/itch
reduction when compared to sham stimulation.


1. Providing informed consent to participate in the study

2. 18 to 64 years old

3. Any size closed wound from burn injury, occurring at least 3 weeks prior to
enrollment in the study.

- Subjects with burns in scalp area will be excluded from the study as the electrode
may cause irritation to the injuries

4. Use of regular medications for pain and/or itching control at stable doses for at
least 3 weeks prior to enrollment in the study

5. No contraindications to tDCS:

- metallic implants in the head

- implanted brain medical devices

6. Subject is not pregnant at the time of enrollment

7. Neuropathic pain or itching (rated at least 4 on the VAS) within the burn scar or
donor site, (pain can be described as burning, stabbing, piercing, pins and needles,
tearing sensation) for at least 3 weeks.

Please note: If a patient reports pain and itching, we will enroll the patient based upon
their most dominant symptom.
We found this trial at
300 1st Avenue
Boston, Massachusetts 02129
Spaulding Rehabilitation Hospital At Spaulding Rehabiliation Hospital Boston, our unique approach to therapy includes use...
Boston, MA
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