Exploration of Parameters of Transcranial Direct Current Stimulation (tDCS) in Chronic Pain

Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Age Range:18 - 64
Start Date:April 2011
Contact:Felipe Fregni, MD, PhD, MPH

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Exploration of Parameters of tDCS in Chronic Pain Patients

The purpose of this study is to assess the effects of high-definition transcranial direct
current stimulation (HD-tDCS) on subjects with chronic musculoskeletal pain. The
investigators hypothesize that subjects will show a decrease in pain symptoms in the active
anodal stimulation group when compared to sham stimulation.


Inclusion Criteria:

1. Providing informed consent to participate in the study

2. 18 to 64 years old

3. Having chronic musculoskeletal pain (existing pain for more than 6 months with an
average of at least 3 on a 0-10 VAS scale)

4. Pain resistant to common analgesics and medications for chronic pain such as Tylenol,
Aspirin, Ibuprofen, Soma, Parafon Forte DCS, Zanaflex, and Codeine.

5. Must have the ability to feel pain as self reported

Exclusion Criteria:

1. Pregnancy

2. Contraindications to tDCS

- metal in the head

- implanted brain medical devices

3. History of alcohol or drug abuse within the past 6 months as self reported

4. Use of carbamazepine within the past 6 months as self reported.

5. Severe depression (with a score of >30 in the Beck Depression Inventory)

6. History of neurological disorders as self reported.

7. History of unexplained fainting spells as self reported,

8. History of head injury resulting in more than a momentary loss of consciousness as
self reported

9. History of neurosurgery as self reported
We found this trial at
300 1st Avenue
Boston, Massachusetts 02129
Spaulding Rehabilitation Hospital At Spaulding Rehabiliation Hospital Boston, our unique approach to therapy includes use...
Boston, MA
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