Prize Contingency Management for Cocaine-Dependent Methadone Patients



Status:Completed
Conditions:Psychiatric, Pulmonary
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - Any
Updated:6/28/2018
Start Date:November 2011
End Date:May 2018

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The investigators will randomize 300 cocaine-dependent methadone patients to 1 of 6
conditions: (a) a control group, (b) a contingency management condition that arranges a 100%
probability of winning a prize with each draw and has 3 prize categories, (c) a contingency
management condition that arranges a 31% probability of winning and has 3 prize categories,
(d) a contingency management condition that arranges a 100% probability of winning and has 7
prize categories, (e) a contingency management condition that arranges a 31% probability of
winning and has 7 prize categories, or (f) usual prize contingency management with a 50%
probability of winning from 3 prize categories. Magnitudes of reinforcement will be identical
across conditions, but lower overall probability conditions arrange for greater chances of
winning larger magnitude prizes. The investigators expect that the new contingency management
conditions will reduce cocaine use relative to the control condition, that 31% probability
conditions will decrease drug use relative to 100% conditions, and that 7-prize category
conditions will reduce drug use compared to 3-prize category conditions. In addition, the
31%/7-category condition is expected to be most efficacious. Results will be instrumental for
further developing prize contingency management to improve outcomes of cocaine-dependent
methadone patients.


Inclusion Criteria:

- age > 18 years

- current DSM-IV diagnosis of cocaine dependence

- enrolled at the clinic for >3 months

- on a stable dose of methadone (no changes) for >1 month and not requesting a dose
alteration

- submitted >1 clinic cocaine positive sample in the last 6 months

- English speaking

- pass a quiz related to understanding the informed consent form

Exclusion Criteria:

- serious, uncontrolled psychiatric illness

- significant cognitive impairment

- in recovery from pathological gambling
We found this trial at
1
site
263 Farmington Ave
Farmington, Connecticut 06030
(860) 679-2000
Principal Investigator: Sheila M Alessi, Ph.D.
Phone: 860-679-4556
University of Connecticut Health Center UConn Health is a vibrant, integrated academic medical center that...
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