Trial of Continuous Versus Interrupted Feeding for Intubated Intensive Care Unit Patients



Status:Completed
Conditions:Food Studies
Therapuetic Areas:Pharmacology / Toxicology
Healthy:No
Age Range:18 - Any
Updated:3/21/2019
Start Date:August 2011
End Date:August 2017

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A Randomized Trial of Continuous Versus Interrupted Enteral Feeding in Critically Ill Surgical Patients Requiring Mechanical Ventilation

Surgical patients fed up until the point of surgery will have safe delivery of more calories
compared to a group whose feeding is held at midnight prior to surgery.

Nutrition is essential for healing and recovery from illness. Tube feeds are the standard
care for patients with prolonged stays in the intensive care unit (ICU) who cannot eat food
on their own. Tube feeding means that a tube has been placed in a patient's stomach or small
intestine to provide nutrition.

When a patient is scheduled for an elective surgery, he/she usually has nothing to eat after
midnight prior to the operation. A fasting period before surgery is done to avoid possible
side effects during the placement of a breathing tube. Having an empty stomach is thought to
decrease the chances of vomiting or aspiration while a breathing tube is placed. (Aspiration
occurs when a substance, such as food provided by a tube feed, enters the airway.) However,
some patients already have a breathing tube in place. The investigators do not know which is
better for patients who already have a breathing tube in place: continuing feedings up until
surgery or stopping them the night before.

The investigators hypothesize intubated surgical patients randomized to a protocol of feeding
up until the point of surgery will have the safe delivery of more calories as compared to a
group whose feeding is held at midnight prior to surgery.

Inclusion Criteria:

- Intubated with planned visit to the OR

- Admitted to an ICU at OHSU

- Receiving enteral nutrition or plan to start enteral nutrition

Exclusion Criteria:

- Age less than 18 years

- Unable to obtain consent from patient or ARR
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