LLLT Combined With CDT in Breast Cancer-Related Lymphedema
| Status: | Completed |
|---|---|
| Conditions: | Breast Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 21 - Any |
| Updated: | 12/8/2017 |
| Start Date: | May 2011 |
| End Date: | July 2017 |
The Effectiveness of Low Level Laser Therapy (LLLT)Combined With Complex Decongestive Therapy (CDT) in the Treatment of Breast Cancer-Related Lymphedema: A Double-Blind, Randomized, Placebo-Controlled Study
This study aims to explore the effects of Low Level Laser Therapy (LLLT) on breast
cancer-related lymphedema when utilized in conjunction with Complex Decongestive Therapy
(CDT) when compared to CDT treatment alone. The investigators hypothesize that the addition
of LLLT to CDT will result in statistically significant improvements and greater long-term
benefits as measured by changes in arm volume and girth, pain levels, tissue texture,
symptoms experienced, and quality of life when compared to the benefits of CDT alone for the
treatment of breast cancer-related lymphedema.
cancer-related lymphedema when utilized in conjunction with Complex Decongestive Therapy
(CDT) when compared to CDT treatment alone. The investigators hypothesize that the addition
of LLLT to CDT will result in statistically significant improvements and greater long-term
benefits as measured by changes in arm volume and girth, pain levels, tissue texture,
symptoms experienced, and quality of life when compared to the benefits of CDT alone for the
treatment of breast cancer-related lymphedema.
Inclusion Criteria:
- unilateral breast cancer with ipsilateral lumpectomy or mastectomy and lymph node
dissection (sentinel biopsy or axillary dissection)
- stage II or III unilateral secondary upper extremity lymphedema (as defined by the
International Society of Lymphology)
- girth ≥ 2 cm circumferential difference and/or volume ≥ 200 mL compared to the
uninvolved upper extremity at any 4 cm segment
- able to commit to a long term follow-up schedule
Exclusion Criteria:
- active cancer/metastatic cancer
- currently receiving or have plans for adjuvant radiation or chemotherapy
- pregnant
- presence of other extremity lymphedema (primary or secondary)
- pacemaker
- artificial joints in the upper quadrants
- renal failure
- arterial insufficiency
- congestive heart failure
- chronic inflammatory conditions
- history of deep vein thrombosis (DVT) in the lymphedematous upper extremity
- previous treatment with Low Level Laser (regardless of indication)
- medication(s) known to affect body fluid balance
- body mass index (BMI) > 40 (morbid obesity)
We found this trial at
3
sites
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials