Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes



Status:Completed
Conditions:Obesity Weight Loss, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:12 - 18
Updated:3/30/2013
Start Date:October 2010
End Date:October 2012
Contact:SoJung Lee, PhD
Email:SoJung.Lee@chp.edu
Phone:412-692-5147

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In this randomized controlled trial, we will examine the effect of a 3-month exercise
training (aerobic exercise versus resistance exercise) without calorie restriction on total
and regional adiposity, ectopic fat in the liver and skeletal muscle, and risk of type 2
diabetes in overweight girls.


Inclusion Criteria:

- Healthy overweight (BMI >-95th) youth between 12 and 18 years of age

- Waist circumference >-75th percentile

- Sedentary (no structured exercise >2 times/week for past 6 months)

- Non-smokers, non-diabetic, no medical conditions

- Weight stable for past 3 months

Exclusion Criteria:

- Smokers

- Diabetes

- Psychiatric disorders

- Syndromic obesity

- Pregnancy

- Taking medications known to affect study outcomes
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