Evaluation for NCI Surgery Branch Clinical Studies



Status:Recruiting
Conditions:Lung Cancer, Colorectal Cancer, Skin Cancer, Cancer, Bladder Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:7 - 70
Updated:12/14/2018
Start Date:July 11, 1999
Contact:Margaret Shovlin, R.N.
Email:IRC@nih.gov
Phone:(866) 820-4505

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Evaluation for NCI Surgery Branch Clinical Research Protocols

Background:

The NCI Surgery Branch has developed experimental therapies that involve taking white blood
cells from patients' tumor or from their blood, growing them in the laboratory in large
numbers, and then giving the cells back to the patient.

Objective:

This study will allow patients to under screening and evaluation for participation in NCI
Surgery Branch Protocols

Eligibility:

Patients must meet the minimum eligibility criteria for an NCI surgery Branch Treatment
Protocol

Design

Patients will undergo testing and evaluations as required by the appropriate NCI Surgery
Branch Treatment protocol

Background:

Potential research candidates undergo thorough screening including laboratory tests, scans,
x-rays and review of pathology slides to determine initial eligibility for Surgery Branch
research protocols.

Objectives:

To permit evaluation of patients referred to the NCI Surgery Branch in order to identify
individuals who will be suitable candidates for Surgery Branch clinical research protocols.

To assess frequency of HLA type, gene specific mutations or expression of neo antigens in
malignant tumors across the population of cancer patients undergoing screening for NCI
Surgery Branch Protocols.

Collect results of screening tests for use on subsequent research protocol as baseline (e.g.,
pretreatment) values.

Eligibility:

Patient suspected of having, or with biopsy proven malignant disease.

Patient, parent or guardian (if a minor), is able to provide informed consent.

Patients who are being evaluated for or treated on NCI Surgery Branch protocols.

Design:

Patients enrolled on this protocol will be evaluated by NCI Surgery Branch physicians to
determine the individual's suitability for participation in a clinical research protocol. An
accrual ceiling of 6000 patients has been set to meet the screening needs of the Surgery
Branch.

- INCLUSION CRITERIA:

Patients suspected of having, or with biopsy proven, malignant disease.

Patients who are being evaluated for or treated on NCI Surgery Branch protocols.

Patient, or their parent(s) legal guardian(s) (if the patient is less than 18 years of
age), is able to understand and willing to sign a written informed consent document. Assent
(verbal or written) will be obtained for participants under the age of 18 as appropriate.

Age greater than 7 and less than 70 years

EXCLUSION CRITERIA:
We found this trial at
1
site
9000 Rockville Pike
Bethesda, Maryland 20892
Phone: 866-820-4505
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from
Bethesda, MD
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