Cardiometabolic Risk of Shiftwork
| Status: | Recruiting |
|---|---|
| Conditions: | Insomnia Sleep Studies |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 4/2/2016 |
| Start Date: | August 2009 |
| Contact: | Lauran DeCeault |
| Email: | ldeceaul@medicine.bsd.uchicago.edu |
| Phone: | 773-834-3144 |
Cardiometabolic Risk of ShiftWork: Sleep Loss vs.Circadian Disruption
The overall goal of the present application is to test the hypothesis that shift workers,
who are chronically exposed to circadian misalignment and sleep loss, have a higher
cardio-metabolic risk than day workers, and that the accumulated sleep debt and the degree
of circadian misalignment both predict their elevated cardio-metabolic risk.
who are chronically exposed to circadian misalignment and sleep loss, have a higher
cardio-metabolic risk than day workers, and that the accumulated sleep debt and the degree
of circadian misalignment both predict their elevated cardio-metabolic risk.
Inclusion Criteria:
- Day workers and shift workers at the University of Chicago, University of Chicago
Medical Center, or another Chicago area medical center who have maintained their work
schedule (at least 30 hours/week) for at least 6 months.
- Individuals who have been shift workers for less than 10 years; body mass index <40
kg/m2;
- No major illness
- No history of psychiatric, endocrine, cardiac or sleep disorders
- Those with hypertension or dyslipidemia will be included if these conditions are
controlled by a stable treatment.
- Women taking oral contraceptive or hormonal replacement therapy will be included only
if they plan to stay on a stable regimen throughout the study.
- Age must be between 18 and 50 years
Exclusion Criteria:
- Individuals who have worked at the University of Chicago, University of Chicago
Medical Center, or another Chicago area medical center in their current position for
less than 6 months.
- Individuals who have been shift workers for more than 10 years
- BMI>40 kg/m2
- Individuals with a major illness (e.g. diabetes, sleep disorder)
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