Once-A-Day Pregabalin For Partial Seizures



Status:Completed
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - Any
Updated:6/7/2018
Start Date:February 17, 2011
End Date:August 1, 2012

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A Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center Trial Of Pregabalin Controlled Release Formulation As Adjunctive Therapy In Adults With Partial Onset Seizures

Approximately 30% percent of subjects with partial seizures are refractory to treatment with
single or combination antiepileptic drugs. The present study will compare the efficacy of two
different dosages of pregabalin CR dosed once daily as compared to placebo, when used as
adjunctive therapy in subjects requiring adjunctive therapy for partial onset epilepsy, using
a randomized, parallel group design.


Inclusion Criteria:

- Diagnosis of epilepsy with partial onset seizures (seizures may be simple or complex,
with or without evolution into a bilateral, convulsive seizure)

- Currently taking 1 to 3 anti-epilepsy medicines (AEDs) at stable dosages, and who have
taken at least 2 prior (or ongoing) AEDs

Exclusion Criteria:

- Primary generalized seizures (for example, absence, myoclonic seizures or
Lennox-Gastaut Syndrome)

- Status epilepticus within one year prior to screening
We found this trial at
27
sites
Murrieta, California 92562
58
mi
from 91732
Murrieta, CA
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1100 N. St. Francis
Wichita, Kansas 67214
316-291-4774
1181
mi
from 91732
Wichita, KS
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Asheville, North Carolina 28806
2000
mi
from 91732
Asheville, NC
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Austin, Texas 78703
1210
mi
from 91732
Austin, TX
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2325 Montañeses
Ciudad Autonoma de Buenos Aires, C1428
6107
mi
from 91732
Ciudad Autonoma de Buenos Aires,
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Gainesville, Florida 32607
2101
mi
from 91732
Gainesville, FL
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Gainesville, Florida 32608
2102
mi
from 91732
Gainesville, FL
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?
mi
from 91732
Gainesville, GA
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Jonesboro, Arkansas 72401
1547
mi
from 91732
Jonesboro, AR
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Lexington, Kentucky 40513
1876
mi
from 91732
Lexington, KY
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Little Rock, Arkansas 72205
1460
mi
from 91732
Little Rock, AR
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Long Beach, California 90806
21
mi
from 91732
Long Beach, CA
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Murrieta, California 92562
55
mi
from 91732
Murrieta, CA
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Northport, Alabama 35476
1744
mi
from 91732
Northport, AL
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Oklahoma City, Oklahoma 73112
1161
mi
from 91732
Oklahoma City, OK
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Oklahoma City, Oklahoma 73134
1161
mi
from 91732
Oklahoma City, OK
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Oklahoma City, Oklahoma 73112
1161
mi
from 91732
Oklahoma City, OK
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3555 NW 58th St # 800
Oklahoma City, Oklahoma 73112
(405) 447-8839
Lynn Health Science Institute Our mission is to provide clinical trials research and health services...
1164
mi
from 91732
Oklahoma City, OK
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Oklahoma City, Oklahoma 73120
?
mi
from 91732
Oklahoma City, OK
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3451 Walnut St
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
2373
mi
from 91732
Philadelphia, PA
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Pikesville, Maryland 21208
2295
mi
from 91732
Pikesville, MD
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Santa Monica, California 90404
26
mi
from 91732
Santa Monica, CA
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801 N Rutledge St
Springfield, Illinois 62702
(217) 545-8000
Southern Illinois University School of Medicine At SIU School of Medicine, research includes biologically oriented...
1608
mi
from 91732
Springfield, IL
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Temecula, California 92591
63
mi
from 91732
Temecula, CA
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1713 Southwest H K Dodgen Loop
Temple, Texas 76502
1217
mi
from 91732
Temple, TX
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Temple, Texas 76508
1211
mi
from 91732
Temple, TX
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Wichita, Kansas 67214
1182
mi
from 91732
Wichita, KS
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