DHEA Against Vaginal Atrophy - Safety Study of 12 Months

Main Inclusion Criteria:

- Postmenopausal women (non-hysterectomized)

- Women between 40 and 75 years of age.

- Willing to participate in the study and sign an informed consent.

- Women who have self-identified symptom(s) of vaginal atrophy.

- Willing to have endometrial biopsy at screening and end of study (Week 52).

Main Exclusion Criteria:

- Undiagnosed abnormal genital bleeding.

- Hypertension equal to or above 140/90 mm Hg.

- The administration of any investigational drug within 30 days of screening visit.

- Endometrial hyperplasia, cancer or endometrial histology showing proliferative,
secretory or menstrual type characteristics at histologic evaluation of endometrial
biopsy performed at screening.