A Study of Ridaforolimus (MK-8669) in Combination With Dalotuzumab (MK-0646) Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients (MK-8669-041)



Status:Archived
Conditions:Breast Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:September 2010
End Date:November 2013

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A Two-Part Adaptive, Randomized Trial of Ridaforolimus in Combination With Dalotuzumab Compared to Exemestane or Compared to Ridaforolimus or Dalotuzumab Monotherapy in Estrogen Receptor Positive Breast Cancer Patients


This is a two-part study that will determine, if: 1) the combination of ridaforolimus and
dalotuzumab will improve progression-free survival compared to exemestane; and 2) the
combination of ridaforolimus and dalotuzumab will improve progression-free survival compared
to both ridaforolimus and dalotuzumab as single agents, in participants with breast cancer.



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Seattle, WA
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Abington, PA
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Asheville, North Carolina 28805
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Camden, NJ
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Las Vegas, NV
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New Britain, Connecticut 06052
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New Britain, CT
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Springfield, Massachusetts 01199
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Springfield, MA
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Springfield, Massachusetts 01199
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Springfield, MA
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