In-Room PET in Proton Radiation Therapy
| Status: | Recruiting |
|---|---|
| Conditions: | Cancer, Brain Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 12/13/2018 |
| Start Date: | October 2010 |
| End Date: | December 2019 |
| Contact: | Tarin Grillo |
| Email: | tgrillo@partners.org |
| Phone: | 617-724-3661 |
Pilot Study of In-Room PET in Proton Radiation Therapy
The investigational part of this study is using a mobile PET/CT scanner to take images of the
participants tumor immediately after they are treated with proton radiation. This allows the
participant to be treated and imaged on the same bed. The information obtained may improve
the accuracy of treatment and may help to minimize the dose delivered unnecessarily to
healthy tissue.
participants tumor immediately after they are treated with proton radiation. This allows the
participant to be treated and imaged on the same bed. The information obtained may improve
the accuracy of treatment and may help to minimize the dose delivered unnecessarily to
healthy tissue.
For all participants, right after one regular treatment fraction, NeuroPET or NeuroPET II
will be wheeled into the patient room. The patient bed will be moved directly into the scan
position and a PET scan will be acquired in list-mode for 15 to 20 minutes followed by a CT
scan for ~5 minutes. After undergoing their first PET scan, participants will have the option
to undergo 1-2 additional scans throughout radiation treatment in the same manner as the
first scan.
will be wheeled into the patient room. The patient bed will be moved directly into the scan
position and a PET scan will be acquired in list-mode for 15 to 20 minutes followed by a CT
scan for ~5 minutes. After undergoing their first PET scan, participants will have the option
to undergo 1-2 additional scans throughout radiation treatment in the same manner as the
first scan.
Inclusion Criteria:
- Adult subjects with brain, head and neck, and skull base tumors receiving external
beam proton radiotherapy at the Francis H. Burr Proton Therapy Center at MGH
- Age 18 or over
- ECOG Performance status 0, 1 or 2
Exclusion Criteria:
- Uncontrolled intercurrent illness that, in the opinion of the investigator, would
limit the participant's compliance with study requirements.
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