Spread of Dermatophytes Among Families



Status:Completed
Conditions:Podiatry
Therapuetic Areas:Orthopedics / Podiatry
Healthy:No
Age Range:14 - Any
Updated:4/2/2016
Start Date:March 2005
End Date:February 2006
Contact:Mahmoud A Ghannoum, PhD
Email:mag3@case.edu
Phone:216-844-8580

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Demonstration of the Spread of Dermatophytes Through Casual Contact Among Family Household Members

The objective is to demonstrate person-to-person spread of dermatophytes of the skin and
nails among family members, as measured by fungal culture and DNA typing of the
dermatophytes isolated.

Enrolled families consist of at least two members over the age of 14. Once the index person
is examined and a dermatophyte is isolated from either toenail or foot scale, other family
members are examined and cultured. All dermatophyte isolates obtained from each family unit
are compared using DNA typing and restriction length polymorphism (RFLP) to determine
whether family members share the same organism or were infected by an outside source.

Inclusion Criteria: positive dermatophyte culture

Exclusion Criteria:

- use of antifungal agents, either oral or topical
We found this trial at
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Cleveland, Ohio 44106
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