Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host Disease



Status:Recruiting
Conditions:Orthopedic, Hematology
Therapuetic Areas:Hematology, Orthopedics / Podiatry
Healthy:No
Age Range:Any
Updated:3/30/2013
Start Date:September 2010
Contact:Jennifer Huang, MD
Email:jennifer.huang@childrens.harvard.edu
Phone:617-355-8937

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The Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host Disease


This research study will help us learn more about how chronic graft-versus-host disease
affects the skin, hair and nails. We are interested in knowing if hair and nail problems
predict worse disease. This information may help us treat patients like you in the future.


- At the initial visit, participants will have a complete examination of their skin, hair
and nails. We will also test muscle strength and movement by moving the participant's
arms, legs and neck. Photographs will be taken of the skin, hair and nails of they are
abnormal. Blood tests will be done to check the liver and blood cell count. The
participant and their legal guardian will answer questions about how the participant
feels and about their health.

- Participants will then be scheduled for follow up visits at 3 months, 6 months, and 12
months. At each subsequent visit the following will be done: A complete examination of
the skin, hair and nails; a test of muscle strength; photographs will be repeated;
blood tests to check liver and blood cell counts; and questions about how the
participant feels and about their health.

Inclusion Criteria:

- Received hematopoietic stem cell transplant

- Meet the diagnostic criteria for cutaneous cGVHD

Exclusion Criteria:

- Previous HSCT (other then the current HSCT)
We found this trial at
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sites
450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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300 Longwood Avenue
Boston, Massachusetts 02115
617-355-6000
Children's Hospital - Boston Boston Children's Hospital is a 395-bed comprehensive center for pediatric health...
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Boston, MA
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