A Four Week, Open-Label Study of Azithromycin Ophthalmic Solution, 1%



Status:Archived
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:November 2010
End Date:April 2011

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A Single-Center, Open-Label Study to Characterize Eyelid Margin Erythema, Markers of Clinical Inflammation and Levels of Inflammatory Mediators in the Lid Margins and Conjunctivae of Untreated Healthy Volunteers and Subjects Diagnosed With Posterior Blepharoconjunctivitis Following Dosing With Azithromycin Ophthalmic Solution, 1% for Four Weeks


One objective of this study is to determine the levels of markers of inflammation on the
eyelid margin of subjects with blepharoconjunctivitis and compare them with those of healthy
volunteers. Another objective is to determine in subjects with blepharoconjunctivitis the
effect of azithromycin ophthalmic solution, 1 % on markers of inflammation of lid margins
and conjunctivae and on signs and symptoms of blepharoconjunctivitis.



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