Impact of Parental Support on Pregnancy Outcomes (IPSO) Trial- Day 3 Preimplantation Genetic Screening (PGS) With Day 5 Fresh Transfer

Status:	Archived
Conditions:	Women's Studies
Therapuetic Areas:	Reproductive
Healthy:	No
Age Range:	Any
Updated:	7/1/2011
Start Date:	September 2010

IPSO Trial - Impact of Parental Support on Pregnancy Outcomes: A Multi-Center, Randomized, Open-Label Study to Evaluate the Implantation and Pregnancy Rates Following 24 Chromosome Aneuploidy Screening With Parental Support in Patients Undergoing In Vitro Fertilization (IVF)

Gene Security Network is recruiting patients for a research study evaluating pregnancy and
implantation rates in women undergoing In Vitro Fertilization (IVF) and Preimplantation
Genetic Screening (PGS). PGS is also referred to as Preimplantation Genetic Diagnosis (PGD)
for aneuploidy.

Healthy women undergoing IVF who are between the ages of 35 to 42 years are being recruited
to participate in a randomized study.

The purpose of this study is to determine whether PGS- testing of embryos created during IVF
for chromosomal abnormalities, prior to transfer to the uterus- improves pregnancy and
implantation rates in patients when compared to patients whose embryos are not tested. PGS
will be conducted using 24 Chromosome Aneuploidy Screening with Parental Support from Gene
Security Network.

All subjects who qualify and enroll will receive discounted IVF medications (both TEST and
CONTROL arms). If you become pregnant during the study, you will receive a small payment for
providing information about your pregnancy and birth. If you are assigned to the TEST arm of
the study you will receive free PGS.

If you meet the criteria below, you may be a candidate for this study. To participate in the
study you must:

- Be a healthy, pre-menopausal female, 35-42 years of age

- Have a history of less than 3 consecutive miscarriages and no more than one failed IVF
cycle

- Agree to use Ferring Pharmaceutical products during stimulation

- Agree to be randomly assigned to either the arm of the study receiving PGS (TEST arm)or
the arm receiving no additional testing (CONTROL arm)

Additional screening will be conducted to determine if you are eligible to enroll.

All subjects who qualify and enroll will receive discounted IVF medications. If you become
pregnant during the study, you will receive a small payment for providing information about
your pregnancy and birth. If you are assigned to the TEST arm of the study you will receive
free PGS.

We found this trial at

sites

The Nevada Center for Reproductive Medicine

Reno, Nevada 89511

from

Reno, NV