HIV Prevention With Adolescents: Neurocognitive Deficits and Treatment Response



Status:Archived
Conditions:Healthy Studies, Psychiatric
Therapuetic Areas:Psychiatry / Psychology, Other
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:October 2007

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This research is examining how genetic and brain factors play a role in adolescents' health
risk behavior as well as studying behaviors that young people engage in that may place them
at risk for contracting a sexually transmitted disease like HIV/AIDS, and what kind of
educational program works best to reduce these risky behaviors.


A baseline assessment is conducted, including a computer questionnaire assessing personality
characteristics, attitudes toward and experiences with sex, alcohol, drugs, and cigarettes,
among other things. The participant also meets with a therapist to conduct a brief
motivational interview at this time. A "Time-Line Follow-Back" is conducted; this notes
incidences of sexual intercourse, alcohol use, marijuana use, and cigarette use in a 30-day
period. An fMRI is conducted, and a saliva sample is gathered. During the second session of
the study, participants are randomly assigned to either a sex and alcohol risk reduction
intervention, or a sex risk reduction intervention. After the intervention, participants are
contacted at 3 month intervals (3 months later, 6 months later, 9 months later, and 12
months later) to meet. At these "follow-up" meetings, another Time-Line Follow-Back is
conducted, along with another computer questionnaire (again assessing attitudes toward and
experiences with sex, alcohol, drugs, and cigarettes).


We found this trial at
4
sites
New Brunswick, New Jersey 08901
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New Brunswick, NJ
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Albuquerque, New Mexico 87107
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Albuquerque, NM
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Albuquerque, New Mexico 87113
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Albuquerque, NM
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Albuquerque, New Mexico 87109
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Albuquerque, NM
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