Genomics of Primary Sclerosing Cholangitis (PSC)
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 5 - 90 |
| Updated: | 12/13/2018 |
| Start Date: | March 2002 |
| End Date: | December 2025 |
P.R.O.G.R.E.S.S.: PSC Resource Of Genetic Risk, Environment and Synergy Studies.
Primary Sclerosing Cholangitis (PSC) is a progressive liver disorder of unknown cause.
Current evidence suggests that genes, the genetic material we inherit from our parents, in
combination with environmental factors, likely play an important role in the development of
PSC.
This study is being done to investigate whether genes make people more likely to develop PSC.
Discovery of these genes will help us to better understand how PSC developes and
subsequently, to apply new approaches for its prevention, diagnosis and treatment.
Current evidence suggests that genes, the genetic material we inherit from our parents, in
combination with environmental factors, likely play an important role in the development of
PSC.
This study is being done to investigate whether genes make people more likely to develop PSC.
Discovery of these genes will help us to better understand how PSC developes and
subsequently, to apply new approaches for its prevention, diagnosis and treatment.
Inclusion Criteria:
- Men, Women, and Children between the ages of 5-90 with a history of PSC.
- PSC patients who have had a liver transplant are eligible.
- Family members (1st degree relatives) of enrolled PSC patients are eligible.
Exclusion Criteria:
- Individuals with no history of PSC or those unable to provide consent.
We found this trial at
1
site
Rochester, Minnesota 55905
Principal Investigator: Konstantinos N Lazaridis, M.D.
Phone: 507-284-4312
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