To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee
| Status: | Archived |
|---|---|
| Conditions: | Arthritis, Osteoarthritis (OA) |
| Therapuetic Areas: | Rheumatology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | April 2010 |
A Randomized, Double Blind, Placebo and Naproxen Controlled, Multi-center, Study to Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee
The study will determine whether the ability of canakinumab to inhibit IL-1β activity for
sustained time-periods with a favorable impact on the three critical parameters of OA
symptoms, namely 1) pain 2) function and 3) stiffness. These outcomes will be compared to
placebo.
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Rush University Medical Center Rush University Medical Center encompasses a 664-bed hospital serving adults and...
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