Continued Safety Monitoring of Solanezumab (LY2062430) in Alzheimer's Disease



Status:Terminated
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:55 - Any
Updated:6/7/2018
Start Date:December 2010
End Date:February 2017

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Continued Efficacy and Safety Monitoring of Solanezumab, an Anti-Amyloid β Antibody in Patients With Alzheimer's Disease

This study is an open-label extension study in Alzheimer's patients who have completed
participation in either solanezumab Clinical Trial H8A-MC-LZAM (NCT00905372) or H8A-MC-LZAN
(NCT00904683).


Inclusion Criteria:

- Meets National Institute of Neurological and Communicative Disorders and
Stroke/Alzheimer's Disease and Related Disorders Association (NINCDS/ADRDA) criteria
for probable Alzheimer's Disease

- Has completed participation in solanezumab Study LZAM or Study LZAN through 80 weeks

- Must continue to have a reliable caregiver who is in frequent contact with the patient
for the entire study

- Must have good vein access to administer infusions

- Agrees not to participate in studies of any other investigational compounds for the
duration of their participation in Study LZAO

Exclusion Criteria:

- Are currently enrolled in, or discontinued within the last 30 days from, a clinical
trial involving an investigational drug or device or off-label use of a drug or device
(other than the study drug/device used in this study), or concurrently enrolled in any
other type of medical research judged not to be scientifically or medically compatible
with this study

- Meets LZAM or LZAN discontinuation criteria at the end of treatment in LZAM or LZAN
study
We found this trial at
65
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Charleston, South Carolina 29412
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East Providence, Rhode Island 02915
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Greer, SC
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