Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec



Status:Archived
Conditions:Colorectal Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:April 2010
End Date:December 2011

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A Dose Finding and Phase II Study of Selumetinib (AZD6244) (Hyd-Sulfate) in Combination With Irinotecan, in 2nd Line Patients With K-ras or B-raf Mutation Positive Advanced or Metastatic Colorectal Cancer


The purpose of this study is to determine whether treatment with Selumetinib (AZD6244)
(Hyd-Sulfate) in combination with Irinotecan as a second treatment in patients with K-ras
or B-raf mutation will prevent tumor progression and prolong progression free survival.


A Dose Finding and Phase II Study of Selumetinib (AZD6244) (Hyd-Sulfate) in Combination
with Irinotecan, in 2nd Line Patients with K-ras or B-raf Mutation Positive Advanced or
Metastatic Colorectal Cancer


We found this trial at
10
sites
2315
mi
from 91732
Fort Lauderdale, FL
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2356
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Allentown, PA
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2002
mi
from 91732
Asheville, NC
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1039
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from 91732
Bellingham, WA
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2436
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from 91732
Bronx, NY
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Chapel Hill, North Carolina
2194
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from 91732
Chapel Hill, NC
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817
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from 91732
Denver, CO
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2486
mi
from 91732
New Haven, CT
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2345
mi
from 91732
Newark, DE
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105
mi
from 91732
San Diego, CA
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