Clopidogrel to Prasugrel in Acute Coronary Syndrome (ACS) Patients



Status:Archived
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:May 2010
End Date:September 2011

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TRansferring From ClopIdogrel Loading Dose to Prasugrel Loading Dose in Acute Coronary Syndrome PatiEnTs: TRIPLET


This study will evaluate the use of a prasugrel 60 mg loading dose (LD) administered during
percutaneous coronary intervention (PCI) with and without a prior LD of clopidogrel on
platelet inhibition in patients presenting with ACS. Platelet inhibition following a
prasugrel LD in clopidogrel pretreated patients' will be determined in a time-dependent
manner for two different prasugrel loading doses (30 mg and 60 mg). Understanding the
effects of this combination on platelet inhibition will provide guidance to physicians on
the use of prasugrel in patients who have already been pretreated with clopidogrel.



We found this trial at
7
sites
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mi
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Lansing, MI
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1 South Prospect Street
Burlington, Vermont 05401
802-656-8990
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mi
from
Burlington, VT
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mi
from
Brooklyn, NY
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mi
from
Miami, FL
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mi
from
Minneapolis, MN
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mi
from
Muskogee, OK
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mi
from
Rapid City, SD
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